Date: Thu Dec 5, 2002 12:40 pm

Subject: interested/expieareance with sam-e? WARNING (please read on)

..sent this letter to Walt today (his question is at the bottem). If this has

made anyone look at thier expieareance of this 'suppliment' differantly, please

tell me, just incase its just paranoia. If its not, then I think others should

know about it, ie please pass it round. Any coments very welcome.

reagrds to all

jason (in france)

ps shame I had to find out on myself...

___________________________________________________

Hia Walt

Nice to hear from u.

Funny you should ask. I took it 4, 4 days at 300mg a day. It over stimulated

me, & dident get rid of the deppression completly. Unfortunatly when I stopped

it made things much, much worse. I now have all the syimptoms that it claims to

help!! joint pains, head aches, my heart & liver hert & the

deppression/anxiety/extream tirerdness are ten times stronger. Im not sure how

much the sam-e has to do with this, but I do get the destinct feeling that if

your body makes all the sam-e it needs (which it dose normaly ie around 8mg a

day, mostly in the liver) supplimenting it makes your liver get lazy, & it

stops producing the amount u supplimented with, ie if u take 100mg a day your

liver goes down 100mg a day naturaly.

I also susspect that if your in wds from antideppresants, it totaly screws up with

the proccess. Three days after I stopped, I got no phisical WD but, my word

did I get psychological ones.. I went into delerious deppression, the bar across

my head became very pronounced, & feel as bad as I did a year ago, with no

windows now. Had begun to get 1 day a week before the sam-e.. make your

own conclussions.

In short, I feel as if not only is my reuptake mecanism srewed up, but now also

the production end of the seratonin/neuroadrenalin/dopamine sinapsis's, that

being that Im not producing anough of those substances, which I can feel

wasent the case before taking sam-e. This is potencialy very danerious because

sam-e is responsable for many chemical functions in the body, including the

correct function of many organs (liver, heart, brain ect).

I may be wrong in this asumption, but if Im not this 'suppliment' should be

avoided at all costs. Can u please do me a faviour & pass this susspition to

the groups your a member of ASAP. It would be interesting to find out how

many of those who have had expieareance with sam-e have also had long term

problems with recovery afterwards, from eighter WDs from antideppresants or

benzo.. so far I have personaly read 3 examples of my susspition, & consider it

of extream importance to find out if my hypothasis is true, so other people can

avoid it.

Am unable to do this myself as Im now so ill again hardly ever go out to write

emails.

Please keep in contact, & my fondest regards to u.

Jason

Walt Berry <WaltBerry@southernfood.net> wrote: Jason,How goes it. I have been

looking for an update from you on the SAMe. Are you still taking it? Is it

helping any? I hope you have seen improvement. Let me know.

Best Wishes,Walt